Wyatt W. Yue, PhD

Wyatt Yue is a structural biologist with an MA in Biochemistry at University of Oxford, and a PhD in Crystallography at Birkbeck College, University of London. He pursued a post-doctoral fellowship in Institute of Cancer Research UK with Prof Laurence Pearl FRS, followed by a stint at the fragment-based drug discovery company Sareum Ltd. In 2008 he joined the Structural Genomics Consortium (SGC), University of Oxford as a Senior Scientist in high throughput protein structure determination. In 2012 he established his own research group ‘Metabolic & Rare Diseases’ at the SGC (www.thesgc.org/mob), applying structural, biochemical, and chemical biology approaches to study diverse metabolic protein families in the human genome. In 2015 he was conferred the title of Associate Professor. He specialises in the use of protein structures and biochemistry to understand the molecular basis of human inherited diseases, with focus in inborn errors of metabolism. He collaborates with front line clinicians and drug developers for the design of small molecule therapy for rare diseases.